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Product details

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1775-100

Price for BNCB1775-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR) . CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP) -activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB1775-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
ABC35; ATP Binding Cassette Superfamily C Member 7 (ABCC7) ; cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Conductance Regulator; MRP7; TNR CFTR
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CFTR
Gene ID
1080
NCBI Gene ID
489786|621460|661104
UniProt
P13569
Swiss Prot
P13569
Host
Rabbit
Species Reactivity
Human
Reactivity
CFTR
Immunogen
Recombinant human CFTR fragment (aa258-385) (exact sequence is proprietary)
Target Antigen
CFTR
Clonality
Recombinant Monoclonal
Clone
CFTR/1775R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Ion channels
Positive Control
MOLT-4 cells. Pancreas, Kidney or Placenta.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
165-170 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG, kappa
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL?

The catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL is BNCB1775-100.

What sizes are available for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL in stock?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), Biotin conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR) . CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) prot

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

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