Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1784-500

Price for BNCB1784-500

Size / count 1x 500 µL

About this product

Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed supealpha-helicalturn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB1784-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: H1 (0) |H1.1|H1.2|H1.3|H1.4|H1.5|H1A|H1F0|H1F1|H1F2|H1F3|H1F4|H1F5|H1FNT|H1FOO|H1FT|H1FV|H1FX|H1t|H1T2|H1X|HANP1|His1|HisC|HIST1|HIST1H1A|HIST1H1B|HIST1H1C|HIST1H1D|HIST1H1E|HIST1H1T|Oocyte-specific histone H1|Testicular H1 histone
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: H1
Gene ID: 3005
NCBI Gene ID: 226117 & 97358
UniProt: Multiple
Swiss Prot: Multiple
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Reactivity: Histone H1
Immunogen: Recombinant full-length human Histone H1 protein
Target Antigen: Histone H1
Clonality: Recombinant Monoclonal
Clone: HH1/1784R
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Organelle markers
Positive Control: HeLa, A-431, LNCap or Jurkat cells. Breast carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~30 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG, kappa
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL?

The catalog number for Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL is BNCB1784-500.

What sizes are available for Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL?

Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL in stock?

Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL?

Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Histone H1 (Nuclear Marker) (HH1/1784R), Biotin conjugate, 0.1mg/mL used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.