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Product details

Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL

Catalog number BNUB1408-500

Price for BNUB1408-500

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Size / count 1x 500 µL

About this product

Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle. Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB1408-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Calponin-1; CNN1; Calponin 1 basic smooth muscle; Calponin H1 smooth muscle
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CNN1
Gene ID
1264
NCBI Gene ID
465929
UniProt
P51911
Swiss Prot
P51911
Host
Rabbit
Species Reactivity
Human, Rat
Reactivity
Calponin-1
Immunogen
Recombinant human full-length CNN1 protein
Target Antigen
Calponin-1
Clonality
Recombinant Monoclonal
Clone
CNN1/1408R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research
Cytoskeleton
Positive Control
Myoepithelial cells in breast ducts
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
34 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG, kappa
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL?

The catalog number for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL is BNUB1408-500.

What sizes are available for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL?

Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL in stock?

Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL?

Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL?

Estimated delivery time for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL?

The safety data sheet for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), 0.2mg/mL used for?

Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing sm

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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