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Product details

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL

Catalog number BNUB1424-100

Price for BNUB1424-100

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Size / count 1x 100 µL

About this product

Caldesmon HMW is the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80 kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This MAb recognizes only the 150 kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB1424-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Caldesmon; Caldesmon 1; Caldesmon 1 Isoform 1; CDM; HCAD
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CALD1
Gene ID
800
NCBI Gene ID
490203
UniProt
Q05682
Swiss Prot
Q05682
Host
Rabbit
Species Reactivity
Human, Rat
Reactivity
Caldesmon, HMW
Immunogen
Recombinant human full-length CALD1 protein
Target Antigen
Caldesmon, HMW
Clonality
Recombinant Monoclonal
Clone
CALD1/1424R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cytoskeleton
Positive Control
Uterus, Blood vessels in all tissues, smooth muscle or leiomyosarcoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
150 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG, kappa
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL?

The catalog number for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL is BNUB1424-100.

What sizes are available for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL?

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL in stock?

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL?

Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL?

Estimated delivery time for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL?

The safety data sheet for Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Caldesmon, HMW (h-Caldesmon) (Smooth Muscle Marker) (CALD1/1424R), 0.2mg/mL used for?

Caldesmon HMW is the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150 kDa) is predominantly expressed in smooth muscle whe

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

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