CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL

Catalog number BNUB1497-500

Price for BNUB1497-500

Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 30-33 kDa, which is identified as CD20. It is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin's disease, particularly of lymphocyte predominant type. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB1497-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: APY; ATOPY; B-lymphocyte cell-surface antigen B1; Bp35; Fc epsilon receptor I beta chain; Fc Fragment of IgE high affinity I receptor for beta polypeptide; FCER1B; High affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IGEL; IGER; IGHER; LEU16; Leukocyte surface antigen Leu-16; Ly44; Membrane spanning 4 domains subfamily A member 2; Membrane-spanning 4-domains subfamily A member 1 (MS4A1)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MS4A1
Gene ID: 931
NCBI Gene ID: 712553
UniProt: P11836
Swiss Prot: P11836
Host: Rabbit
Species Reactivity: Human
Reactivity: CD20
Immunogen: Recombinant human full-length MS4A1 protein
Target Antigen: CD20
Clonality: Recombinant Monoclonal
Clone: IGEL/1497R
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IHC, FFPE (verified)
Field of Research: Immunology
Positive Control: Daudi, Raji, and U266, and human lymphocytes. Lymph nodes and tonsils.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 33-37 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG, kappa
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL?

The catalog number for CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL is BNUB1497-500.

What sizes are available for CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL?

CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL in stock?

CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL?

CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL?

Estimated delivery time for CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL?

The safety data sheet for CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD20 / MS4A1 (B-Cell Marker) (IGEL/1497R), 0.2mg/mL used for?

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.