CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL

Catalog number BNUB1506-100

Price for BNUB1506-100

Size / count 1x 100 µL

About this product

At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB1506-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cortical thymocyte antigen CD1A, Epidermal dendritic cell marker CD1a antibody, FCB6, HTA1, T cell surface antigen T6 / Leu 6, T-Cell Surface Glycoprotein CD1A
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD1A
Gene ID: 909
NCBI Gene ID: 1309
UniProt: P06126
Swiss Prot: P06126
Host: Rabbit
Species Reactivity: Human
Reactivity: CD1a|HTA1
Immunogen: Recombinant human full-length CD1a protein
Target Antigen: CD1a | HTA1
Clonality: Recombinant Monoclonal
Clone: C1A/1506R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 49 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG, kappa
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL?

The catalog number for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL is BNUB1506-100.

What sizes are available for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL?

CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL in stock?

CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL?

CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL?

Estimated delivery time for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL?

The safety data sheet for CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD1a / HTA1 (Mature Langerhans Cells Marker) (C1A/1506R), 0.2mg/mL used for?

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.