CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL

Catalog number BNUB1775-500

Price for BNUB1775-500

Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 165-170 kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR) . CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP) -activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB1775-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ABC35; ATP Binding Cassette Superfamily C Member 7 (ABCC7) ; cAMP-dependent chloride channel; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; Cystic Fibrosis Transmembrane Conductance Regulator; MRP7; TNR CFTR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CFTR
Gene ID: 1080
NCBI Gene ID: 489786|621460|661104
UniProt: P13569
Swiss Prot: P13569
Host: Rabbit
Species Reactivity: Human
Reactivity: CFTR
Immunogen: Recombinant human CFTR fragment (aa258-385) (exact sequence is proprietary)
Target Antigen: CFTR
Clonality: Recombinant Monoclonal
Clone: CFTR/1775R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Ion channels
Positive Control: MOLT-4 cells. Pancreas, Kidney or Placenta.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 165-170 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG, kappa
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL?

The catalog number for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL is BNUB1775-500.

What sizes are available for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL in stock?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL?

CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL?

Estimated delivery time for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL?

The safety data sheet for CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) (CFTR/1775R), 0.2mg/mL used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.