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Product details

Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL

Catalog number BNUB1782-100

Price for BNUB1782-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 75 kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposi's sarcoma, angiosarcoma, and epithelioid hemangioendothelioma) . Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB1782-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
AHUS6; BDCA3; CD141; Fetomodulin; Thbd; THPH12; THRM; Thrombomodulin (TM)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
THBD
Gene ID
7056
NCBI Gene ID
2030
UniProt
P07204
Swiss Prot
P07204
Host
Mouse
Species Reactivity
Human
Reactivity
CD141|Thrombomodulin
Immunogen
Recombinant human Thrombomodulin protein fragment (aa69-194) (exact sequence is proprietary)
Target Antigen
CD141 | Thrombomodulin
Clonality
Monoclonal
Clone
THBD/1782
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer
Positive Control
THP1 Cells. Placenta, Angiosarcoma, Bladder or Cervical Carcinoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL?

The catalog number for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL is BNUB1782-100.

What sizes are available for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL?

Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL in stock?

Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL?

Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL?

Estimated delivery time for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL?

The safety data sheet for Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Thrombomodulin / CD141 (Endothelial Cell Marker) (THBD/1782), 0.2mg/mL used for?

This antibody recognizes a protein of 75 kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and sync

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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