Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL

Catalog number BNUM1825-50

Price for BNUM1825-50

Size / count 1x 50 µL

About this product

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM1825-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SILV
Gene ID: 6490
NCBI Gene ID: 95972
UniProt: P40967
Swiss Prot: P40967
Host: Rabbit
Species Reactivity: Human
Reactivity: Gp100|Melanosome|Pmel17|SILV
Immunogen: Recombinant full-length human SILV protein
Target Antigen: gp100 | Melanosome | Pmel17 | SILV
Clonality: Recombinant Monoclonal
Clone: PMEL/1825R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer
Positive Control: SK-MEL-28 cells or Melanoma
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 90-100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG, kappa
Species: Oryctolagus cuniculus (domestic rabbit)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL?

The catalog number for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL is BNUM1825-50.

What sizes are available for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL in stock?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL?

Estimated delivery time for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL?

The safety data sheet for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), 1mg/mL used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.