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Product details

Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL

Catalog number BNUM1866-50

Price for BNUM1866-50

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Size / count 1x 50 µL

About this product

Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle. Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM1866-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Calponin-1; CNN1; Calponin 1 basic smooth muscle; Calponin H1 smooth muscle
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CNN1
Gene ID
1264
NCBI Gene ID
465929
UniProt
P51911
Swiss Prot
P51911
Host
Mouse
Species Reactivity
Human, Rat
Reactivity
Calponin-1
Immunogen
Recombinant full-length human CNN1 protein
Target Antigen
Calponin-1
Clonality
Recombinant Monoclonal
Clone
RCNN1/832
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cytoskeleton
Positive Control
Myoepithelial cells in breast ducts
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
34 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL?

The catalog number for Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL is BNUM1866-50.

What sizes are available for Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL?

Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL in stock?

Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL?

Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL?

Estimated delivery time for Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL?

The safety data sheet for Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Calponin-1 (Smooth Muscle Marker) (rCNN1/832), 1mg/mL used for?

Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing sm

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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