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Product details

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL

Catalog number BNUB2299-100

Price for BNUB2299-100

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Size / count 1x 100 µL

About this product

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. This MAb is excellent for staining of formalin-fixed, paraffin-embedded breast carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2299-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Estrogen Receptor alpha delta 4*5,6,7*/654 isoform; Estrogen Receptor alpha delta 4 49 isoform; Nuclear receptor subfamily 3 group A member 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
ESR1
Gene ID
2099
NCBI Gene ID
208124
UniProt
P03372
Swiss Prot
P03372
Host
Rabbit
Species Reactivity
Human
Reactivity
Estrogen Receptor, alpha
Immunogen
Recombinant full-length human Estrogen Receptor alpha protein
Target Antigen
Estrogen Receptor, alpha
Clonality
Recombinant Monoclonal
Clone
ESR1/2299R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Endocrinology, Nuclear receptors
Positive Control
MCF-7 Cells or Breast Cancers.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
67 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL?

The catalog number for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL is BNUB2299-100.

What sizes are available for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL in stock?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL?

Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL?

Estimated delivery time for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL?

The safety data sheet for Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Estrogen Receptor, alpha (Marker of Estrogen Dependence) (ESR1/2299R), 0.2mg/mL used for?

This MAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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