Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL — image 1 of 2

Product details

Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL

Catalog number BNUB2313-100

Price for BNUB2313-100

Size / count 1x 100 µL

About this product

This antibody recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB2313-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: OSRC; Osteosarcoma; p105-Rb; PP105; pp110; pRb; Prepro retinoblastoma associated protein; RB1; Retinoblastoma 1; Retinoblastoma-associated protein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: RB1
Gene ID: 5925
NCBI Gene ID: 408528
UniProt: P06400
Swiss Prot: P06400
Host: Rabbit
Species Reactivity: Human, Mouse
Reactivity: Rb1
Immunogen: Recombinant full-length human Rb1 protein
Target Antigen: Rb1
Clonality: Recombinant Monoclonal
Clone: RB1/2313R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Tumor suppressors
Positive Control: HeLa, A431 or BT-20 cells. Breast or Colon carcinoma.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 105 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL?

The catalog number for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is BNUB2313-100.

What sizes are available for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL in stock?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL?

Estimated delivery time for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL?

The safety data sheet for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.