Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL

Catalog number BNUB1600-100

Price for BNUB1600-100

Size / count 1x 100 µL

About this product

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI <5.7) and basic (pI >6.0) subfamilies. This antibody cocktail recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, which 67 kDa (CK1) ; 64 kDa (CK3) ; 59 kDa (CK4) ; 58 kDa (CK5) ; 56 kDa (CK6) ; 52 kDa (CK8) ; 56.5 kDa (CK10) ; 50 kDa (CK14) ; 50 kDa (CK15) ; 48 kDa (CK16) ; 40 kDa (CK19) . Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. It is a broad spectrum anti pan-cytokeratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer. It may be useful to characterize the source of various neoplasms and to study the distribution of cytokeratin containing cells in epithelia during normal development and during the development of epithelial neoplasms. This antibody stains cytokeratins present in normal and abnormal human tissues and has high sensitivity in the recognition of epithelial cells and carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB1600-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: K1B; KRT1B; Keratin; type II cytoskeletal 1b; K77; CK-1B; Keratin 1B; Keratin-77; Cytokeratin-1B; Type-II Keratin Kb39
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KRT77; KRT76
Gene ID: 374454; 51350
NCBI Gene ID: 334989 ; 654392
UniProt: Q7Z794; Q01546
Swiss Prot: Q7Z794 ; Q01546
Host: Rabbit
Species Reactivity: Human
Reactivity: Cytokeratin, pan
Immunogen: Recombinant full-length human KRT76 and KRT77 proteins
Target Antigen: Cytokeratin, pan
Clonality: Recombinant Monoclonal
Clone: KRTH/1576R KRTL/1577R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Cytoskeleton
Positive Control: Skin, Adeno- or Squamous carcinomas
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 40-67 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL?

The catalog number for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL is BNUB1600-100.

What sizes are available for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL?

Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL in stock?

Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL?

Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL?

Estimated delivery time for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL?

The safety data sheet for Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin, pan (Epithelial Marker) (KRTH/1576R + KRTL/1577R), 0.2mg/mL used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.