Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL — image 1 of 4

Product details

Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL

Catalog number BNUB2403-100

Price for BNUB2403-100

Size / count 1x 100 µL

About this product

Granzyme B is a member of the granule serine protease family stored specifically in NK cells or cytotoxic T cells. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTLs in the cell-mediated immune response. Granzyme B is useful as a marker in the identification of NK/T-cell lymphomas. High percentages of cytotoxic T-cells have been shown to be an unfavorable prognostic indicator in Hodgkin's Disease.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB2403-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cathepsin G-like 1; CCPI; CGL1; CSPB; CTLA-1; CTSGL1; Cytotoxic serine protease B; Cytotoxic T lymphocyte associated serine esterase 1; Cytotoxic T-lymphocyte proteinase 2; Fragmentin-2; Granzyme B; Granzyme-2; GRB; Gzmb; Human lymphocyte protein (Hlp) ; Lymphocyte protease; SECT; T-cell serine protease 1-3E
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: GZMB
Gene ID: 3002
NCBI Gene ID: 1051
UniProt: P10144
Swiss Prot: P10144
Host: Mouse
Species Reactivity: Human
Reactivity: Granzyme B
Immunogen: Recombinant fragment of human GZMB protein (around aa 73-187) (exact sequence is proprietary)
Target Antigen: Granzyme B
Clonality: Monoclonal
Clone: GZMB/2403
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Immunology
Positive Control: A431 cells. Tonsil, Spleen or Hodgkin's Lymphoma
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 29-32 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL?

The catalog number for Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL is BNUB2403-100.

What sizes are available for Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL?

Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL in stock?

Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL?

Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL?

Estimated delivery time for Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL?

The safety data sheet for Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e1007c6/msds/bnub2403-100.pdf.

What is Granzyme B (NK/T-Cell Lymphoma Marker) (GZMB/2403), 0.2mg/mL used for?

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.