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Product details

Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL

Catalog number BNUB2050-100

Price for BNUB2050-100

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Size / count 1x 100 µL

About this product

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2050-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGKC
Gene ID
3514
NCBI Gene ID
449609
UniProt
P01601; P01834
Swiss Prot
P01601 & P01834
Host
Mouse
Species Reactivity
Human
Reactivity
Human Kappa Light Chain
Immunogen
Recombinant full-length human Ig kappa chain
Target Antigen
Human Kappa Light Chain
Clonality
Monoclonal
Clone
RKLC709
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Immunology, Inflammation
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
~22.5 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL?

The catalog number for Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL is BNUB2050-100.

What sizes are available for Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL?

Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL in stock?

Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL?

Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL?

Estimated delivery time for Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL?

The safety data sheet for Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Human Kappa Light Chain / IGKC (B-Cell Marker) (rKLC709), 0.2mg/mL used for?

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two li

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

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