• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL

Catalog number BNUB2039-100

Price for BNUB2039-100

Sign In for Pricing

Size / count 1x 100 µL

About this product

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2039-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
95kDa melanocyte-specific secreted glycoprotein, M-beta; Melanocyte lineage specific antigen GP100; Melanocyte protein Pmel 17; Melanoma associated ME20 antigen; Melanosomal matrix protein17; Premelanosome protein (PMEL17) ; Secreted melanoma-associated ME20 antigen; SILV; Silver homolog
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SILV
Gene ID
6490
NCBI Gene ID
95972
UniProt
P40967
Swiss Prot
P40967
Host
Mouse
Species Reactivity
Human
Reactivity
Gp100|Melanosome|Pmel17|SILV
Immunogen
Recombinant human SILV protein fragment (around aa 376-502) (exact sequence is proprietary)
Target Antigen
gp100 | Melanosome | Pmel17 | SILV
Clonality
Monoclonal
Clone
PMEL/2039
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer
Positive Control
SK-MEL-28 cells or Melanoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
90-100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL?

The catalog number for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL is BNUB2039-100.

What sizes are available for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL in stock?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL?

Estimated delivery time for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL?

The safety data sheet for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/2039), 0.2mg/mL used for?

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

You Might Also Like
CD81 / TAPA-1 (1.3.3.22), CF647 conjugate, 0.1mg/mL
CD81 / TAPA-1 (1.3.3.22), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470391-100
TGF-beta (1D11.16.8), CF740 conjugate, 0.1mg/mL
TGF-beta (1D11.16.8), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740977-500
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF594 conjugate, 0.1mg/mL
CD171 / L1CAM (L1 Cell Adhesion Molecule) (UJ127), CF594 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC940679-500
ACTH (Adrenocorticotrophic Hormone) (AH26), CF740 conjugate, 0.1mg/mL
ACTH (Adrenocorticotrophic Hormone) (AH26), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740026-500
CD3e (B-B12), CF640R conjugate, 0.1mg/mL
CD3e (B-B12), CF640R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC401052-100
FOXP3 (3G3), CF488A conjugate, 0.1mg/mL
FOXP3 (3G3), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880645-100
CD1a (O10 + C1A/711), CF647 conjugate, 0.1mg/mL
CD1a (O10 + C1A/711), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470717-500
WT1 (Wilm's Tumor 1) (WT1/857), CF405S conjugate, 0.1mg/mL
WT1 (Wilm's Tumor 1) (WT1/857), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040857-100