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Product details

Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL

Catalog number BNUB2030-500

Price for BNUB2030-500

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Size / count 1x 500 µL

About this product

Beta-catenin associates with the cytoplasmic portion of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions. Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways, and is also found in complexes with many different proteins including the tumor suppressor protein APC. Defects in beta-catenin are associated with colorectal cancer, as well as many other cancer types. Beta-catenin is normally localized to the cell membrane, but can translocate to the nucleus in response to certain cell signaling. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2030-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Beta-catenin; Catenin beta-1; Catenin (Cadherin associated protein), beta 1; CTNNB
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CTNNB1
Gene ID
1499
NCBI Gene ID
476018
UniProt
P35222
Swiss Prot
P35222
Host
Rabbit
Species Reactivity
Human
Reactivity
Beta-catenin|Catenin, Beta
Immunogen
Recombinant full-length human Î2-catenin protein
Target Antigen
Beta-catenin | Catenin, Beta
Clonality
Recombinant Monoclonal
Clone
CTNNB1/2030R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Cell adhesion, Developmental biology, Signal transduction
Positive Control
HeLa or MCF-7 cells. Breast carcinoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
92 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL?

The catalog number for Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL is BNUB2030-500.

What sizes are available for Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL?

Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL in stock?

Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL?

Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL?

Estimated delivery time for Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL?

The safety data sheet for Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Catenin, beta (CTNNB1) (CTNNB1/2030R), 0.2mg/mL used for?

Beta-catenin associates with the cytoplasmic portion of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions. Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways, and is also found in complex

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

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