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Product details

HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL

Catalog number BNUB2967-500

Price for BNUB2967-500

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Size / count 1x 500 µL

About this product

This antibody reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2967-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HLA-DP; HLA-DQ; HLA-DR
Gene ID
3115 (HLA-DP); 3117 (HLA-DQ); 3122 (HLA-DR)
NCBI Gene ID
347270 (HLA-DP); 550475 (HLA-DQ); 520048 (HLA-DR)
UniProt
P04440 (HLA-DP); P01908; P01909; P01920 (HLA-DQ); P01903 (HLA-DR)
Swiss Prot
P04440 (HLA-DP) ; P01908; P01909; P01920 (HLA-DQ) ; P01903 (HLA-DR)
Host
Rabbit
Species Reactivity
Human
Reactivity
HLA-DP/-DQ/-DR
Immunogen
Non-T, non-B human acute lymphoblastic leukemia REH6 cell line
Target Antigen
HLA-DP/-DQ/-DR
Clonality
Recombinant Monoclonal
Clone
HLA-Pan/2967R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Immunology, MHC antigens
Positive Control
Raji cells. Tonsil or lymph node
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
33-35 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL?

The catalog number for HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL is BNUB2967-500.

What sizes are available for HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL?

HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL in stock?

HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL?

HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL?

Estimated delivery time for HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL?

The safety data sheet for HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is HLA-Pan (MHC II) (HLA-Pan/2967R), 0.2mg/mL used for?

This antibody reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting ce

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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