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Product details

FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL

Catalog number BNUB2230-500

Price for BNUB2230-500

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Size / count 1x 500 µL

About this product

The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (alpha and beta), HNF-3 (alpha, beta and gamma), HNF-4 (alpha and gamma), and HNF-6 compose, in part, a homeoprotein family designated the hepatocyte nuclear factor family. The various HNF-1 isoforms regulate transcription of genes in the liver as well as in other tissues such as kidney, small intestine and thymus. FOXA1 is expressed in normal breast ductal epithelium and other epithelium in different organs, such as lung, pancreas, bladder, prostate, and colon. Recently, FOXA1 has been shown to be a major determinant of estrogen-ER activity and endocrine response in breast cancer cells. FOXA1 expression correlates with estrogen receptor (ER) -positivity, especially in luminal subtype A breast cancers, which is associated with favorable prognosis. FOXA1 is useful in the sub-classification of breast carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2230-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Forkhead box protein A1 (FOXA1) ; Hepatocyte nuclear factor 3-alpha (HNF-3-alpha or HNF-3A or HNF3A) ; Transcription factor 3A (TCF-3A or TCF3A)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
FOXA1
Gene ID
3169
NCBI Gene ID
163484
UniProt
P55317
Swiss Prot
P55317
Host
Rabbit
Species Reactivity
Human, Rat
Reactivity
FOXA1|HNF3A
Immunogen
Recombinant human FOXA1 protein fragment (around aa372-472) (exact sequence is proprietary)
Target Antigen
FOXA1 | HNF3A
Clonality
Recombinant Monoclonal
Clone
FOXA1/2230R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Developmental biology, Endocrinology, Transcription factors
Positive Control
HepG-2 or MCF-7 cells. Liver, Pancreas, Bladder, Prostate, Colon and Lung and Breast.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
49 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL?

The catalog number for FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL is BNUB2230-500.

What sizes are available for FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL?

FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL in stock?

FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL?

FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL?

Estimated delivery time for FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL?

The safety data sheet for FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e1009bf/msds/bnub2230-500.pdf.

What is FOXA1 / HNF3A (FOXA1/2230R), 0.2mg/mL used for?

The transcription factor Forkhead-box A1 (FOXA1), also known as hepatocyte nuclear factor 3-alpha, is a member of the FOX class of transcription factors. HNF-1 (alpha and beta), HNF-3 (alpha, beta and gamma), HNF-4 (alpha and gamma), and HNF-6 compose, in part, a homeoprotein family designated the h

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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