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Product details

Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL

Catalog number BNUB2651-500

Price for BNUB2651-500

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Size / count 1x 500 µL

About this product

Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2651-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cytokine Synthesis Inhibitory Factor (CSIF) ; GVHDS; IL-10; IL10; IL10A; Interleukin-10; T-cell Growth Inhibitory Factor (TGIF)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IL10
Gene ID
3586
NCBI Gene ID
193717
UniProt
P22301
Swiss Prot
P22301
Host
Rabbit
Species Reactivity
Human
Reactivity
Interleukin 10
Immunogen
Recombinant full-length human Interleukin 10 (IL10) protein
Target Antigen
Interleukin 10
Clonality
Recombinant Monoclonal
Clone
IL10/2651R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cytokines, Immunology, Inflammation
Positive Control
SK-BR3 Cells. Adrenal, Lymph Node, Bladder, Prostate or Endometrium.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
20 kDa (Monomer) ; 37 kDa (Dimer)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL?

The catalog number for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL is BNUB2651-500.

What sizes are available for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL?

Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL in stock?

Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL?

Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL?

Estimated delivery time for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL?

The safety data sheet for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), 0.2mg/mL used for?

Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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