Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL — image 1 of 2

Product details

Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL

Catalog number BNUB2313-500

Price for BNUB2313-500

Size / count 1x 500 µL

About this product

This antibody recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB2313-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: OSRC; Osteosarcoma; p105-Rb; PP105; pp110; pRb; Prepro retinoblastoma associated protein; RB1; Retinoblastoma 1; Retinoblastoma-associated protein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: RB1
Gene ID: 5925
NCBI Gene ID: 408528
UniProt: P06400
Swiss Prot: P06400
Host: Rabbit
Species Reactivity: Human, Mouse
Reactivity: Rb1
Immunogen: Recombinant full-length human Rb1 protein
Target Antigen: Rb1
Clonality: Recombinant Monoclonal
Clone: RB1/2313R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Tumor suppressors
Positive Control: HeLa, A431 or BT-20 cells. Breast or Colon carcinoma.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 105 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL?

The catalog number for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is BNUB2313-500.

What sizes are available for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL in stock?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL?

Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL?

Estimated delivery time for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL?

The safety data sheet for Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Rb1 (Tumor Suppressor Protein) (RB1/2313R), 0.2mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.