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Product details

TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL

Catalog number BNUB2946-500

Price for BNUB2946-500

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Size / count 1x 500 µL

About this product

Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2946-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Enhancer of split groucho 1 (ESG1) ; Enhancer of split groucho-like protein 1; GRG1; TLE1; Transducin like enhancer of split 1; Transducin-like enhancer protein 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TLE1
Gene ID
7088
NCBI Gene ID
197320; 689805
UniProt
Q04724
Swiss Prot
Q04724
Host
Rabbit
Species Reactivity
Human
Reactivity
TLE1
Immunogen
Recombinant human TLE1 fragment (aa 175-338) (exact sequence is proprietary)
Target Antigen
TLE1
Clonality
Recombinant Monoclonal
Clone
TLE1/2946R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology, Transcription factors
Positive Control
HeLa, HepG2 or Jurkat cells. Endometrium Carcinoma or Sarcomas
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
83 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL?

The catalog number for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL is BNUB2946-500.

What sizes are available for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL?

TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL in stock?

TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL?

TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL?

Estimated delivery time for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL?

The safety data sheet for TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TLE1 (Synovial Sarcoma Marker) (TLE1/2946R), 0.2mg/mL used for?

Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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