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Product details

CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL

Catalog number BNUB2990-500

Price for BNUB2990-500

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Size / count 1x 500 µL

About this product

This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with specific integrins. The tetraspanin CD63 is a lysosomal membrane glycoprotein that translocates to the plasma membrane after platelet activation. CD63 is expressed on activated platelets, monocytes and macrophages, and is weakly expressed on granulocytes, T cell and B cells. It is located on the basophilic granule membranes and on the plasma membranes of lymphocytes and granulocytes. CD63 is a member of the TM4 superfamily of leukocyte glycoproteins that includes CD9, CD37 and CD53, which contain four transmembrane regions. CD63 may play a role in phagocytic and intracellular lysosome-phagosome fusion events. CD63 deficiency is associated with Hermansky-Pudlak syndrome and is strongly expressed during the early stages of melanoma progression.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2990-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Gp55; granulophysin; Lysosomal-associated membrane protein 3 (LAMP-3) ; Mast cell antigen AD1; melanoma 1 antigen; Melanoma-associated antigen MLA1; Melanoma-associated antigen ME491; MLA1; NGA; Ocular melanoma-associated antigen; OMA81H; PTLGP40; Tetraspanin-30; TSPAN30
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD63
Gene ID
967
NCBI Gene ID
445570
UniProt
P08962
Swiss Prot
P08962
Host
Rabbit
Species Reactivity
Human
Reactivity
CD63
Immunogen
Recombinant full-length human CD63 protein
Target Antigen
CD63
Clonality
Recombinant Monoclonal
Clone
LAMP3/2990R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IHC, FFPE (verified)
Field of Research
Cancer, Immunology
Positive Control
U87MG, SK-MEL-28, HL60, THP-1, NIH/3T3, or MCF-7 cells. Human melanoma, spleen or lymphoma tissue.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
26 kDa (core protein) ; 30-60 kDa (glycosylated)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL?

The catalog number for CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL is BNUB2990-500.

What sizes are available for CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL?

CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL in stock?

CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL?

CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL?

Estimated delivery time for CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL?

The safety data sheet for CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD63 (Late Endosomes Marker) (LAMP3/2990R), 0.2mg/mL used for?

This MAb recognizes protein of 26 kDa-60 kDa, which is identified as CD63. Its epitope is different from that of MAb LAMP3/529. The tetraspanins are integral membrane proteins expressed on cell surface and granular membranes of hematopoietic cells and are components of multi-molecular complexes with

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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