- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
Product details
Catalog number BNUB2111-500
Price for BNUB2111-500
Size / count 1x 500 µL
The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes mutS and mutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. A member of the mismatch repair family, GTBP (also designated MSH6), is an MSH2-related protein that binds to DNA containing G/T mismatches. Findings suggest that the mismatch-binding factor in human cells is composed of a heterodimer of GTBP and MSH2.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), 0.2mg/mL is BNUB2111-500.
MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), 0.2mg/mL is available in the following size(s): 1x 500 µL.
MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for MSH6 (DNA Mismatch Repair Protein) (MSH6/2111), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacter
Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.
Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.
Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.
