Product details
Catalog number BNUB2089-500
Price for BNUB2089-500
Size / count 1x 500 µL
Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. SOD-1 is ubiquitously expressed in somatic cells and functions as a homodimer. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases, including amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by the loss of spinal motor neurons, Down syndrome and Alzheimer s disease. In familial ALS, several mutations in SOD-1 predominate, resulting in the loss of zinc binding, the loss of scavenging activity of SOD-1, and correlate with an increase in neurotoxicity and motor neuron death.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is BNUB2089-500.
Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is available in the following size(s): 1x 500 µL.
Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
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