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Product details

Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL

Catalog number BNUB2089-500

Price for BNUB2089-500

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Size / count 1x 500 µL

About this product

Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. SOD-1 is ubiquitously expressed in somatic cells and functions as a homodimer. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases, including amyotrophic lateral sclerosis (ALS), a neurodegenerative disease characterized by the loss of spinal motor neurons, Down syndrome and Alzheimer s disease. In familial ALS, several mutations in SOD-1 predominate, resulting in the loss of zinc binding, the loss of scavenging activity of SOD-1, and correlate with an increase in neurotoxicity and motor neuron death.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2089-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Amyotrophic lateral sclerosis 1 (ALS1) ; Cu/Zn SOD; Cu/Zn Superoxide Dismutase; Epididymis Secretory Protein Li 44; Indophenoloxidase A (IPOA) ; Superoxide Dismutase [Cu-Zn]; Superoxide Dismutase 1 (SOD1)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SOD1
Gene ID
6647
NCBI Gene ID
443914
UniProt
P00441
Swiss Prot
P00441
Host
Mouse
Species Reactivity
Human
Reactivity
Superoxide Dismutase 1
Immunogen
Recombinant full-length human SOD1 protein
Target Antigen
Superoxide Dismutase 1
Clonality
Monoclonal
Clone
SOD1/2089
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Free radicals, Metabolism
Positive Control
HeLa or Jurkat Cells. Breast or Ovarian carcinoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
23 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL?

The catalog number for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is BNUB2089-500.

What sizes are available for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL?

Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL in stock?

Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL?

Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL?

Estimated delivery time for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL?

The safety data sheet for Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Superoxide Dismutase 1 (SOD1) (Antioxidant Enzyme) (SOD1/2089), 0.2mg/mL used for?

Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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