TLE1 (Synovial Sarcoma Marker) (TLE1/2062), 0.2mg/mL — image 1 of 5

Product details

TLE1 (Synovial Sarcoma Marker) (TLE1/2062), 0.2mg/mL

Catalog number BNUB2062-500

Price for BNUB2062-500

Size / count 1x 500 µL

About this product

Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB2062-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Enhancer of split groucho 1 (ESG1) ; Enhancer of split groucho-like protein 1; GRG1; TLE1; Transducin like enhancer of split 1; Transducin-like enhancer protein 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TLE1
Gene ID: 7088
NCBI Gene ID: 197320; 689805
UniProt: Q04724
Swiss Prot: Q04724
Host: Mouse
Species Reactivity: Human
Reactivity: TLE1
Immunogen: Recombinant human TLE1 fragment (aa 175-338) (exact sequence is proprietary)
Target Antigen: TLE1
Clonality: Monoclonal
Clone: TLE1/2062
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Developmental biology, Transcription factors
Positive Control: HeLa, HepG2 or Jurkat cells. Endometrium Carcinoma or Sarcomas
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 83 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

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