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Product details
Catalog number BNUB1925-500
Price for BNUB1925-500
Size / count 1x 500 µL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53 protein. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast carcinoma, lung carcinoma, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in a wide variety of malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for P53 Tumor Suppressor Protein (PCRP-TP53-1F7), 0.2mg/mL is BNUB1925-500.
P53 Tumor Suppressor Protein (PCRP-TP53-1F7), 0.2mg/mL is available in the following size(s): 1x 500 µL.
P53 Tumor Suppressor Protein (PCRP-TP53-1F7), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
P53 Tumor Suppressor Protein (PCRP-TP53-1F7), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for P53 Tumor Suppressor Protein (PCRP-TP53-1F7), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for P53 Tumor Suppressor Protein (PCRP-TP53-1F7), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53
Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.
A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
