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Product details
Catalog number BNUB1739-500
Price for BNUB1739-500
Size / count 1x 500 µL
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. It is a tumor suppressor protein expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognostic factor in breast, lung, colorectal, and urothelial carcinoma. Anti-p53 positivity has also been used to differentiate uterine serous carcinoma from endometrioid carcinoma as well as to detect intratubular germ cell neoplasia. Mutations involving p53 are found in many malignant tumors, including breast, ovarian, bladder, colon, lung, and melanoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for P53 Tumor Suppressor Protein (TP53/1739), 0.2mg/mL is BNUB1739-500.
P53 Tumor Suppressor Protein (TP53/1739), 0.2mg/mL is available in the following size(s): 1x 500 µL.
P53 Tumor Suppressor Protein (TP53/1739), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
P53 Tumor Suppressor Protein (TP53/1739), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for P53 Tumor Suppressor Protein (TP53/1739), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for P53 Tumor Suppressor Protein (TP53/1739), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101db1/msds/bnub1739-500.pdf.
The specificity of this monoclonal antibody to its intended target was validated by HuProt™ Array, containing more than 19,000, full-length human proteins. Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p5
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.
Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.
Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.
