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Product details

P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL

Catalog number BNUB2427-500

Price for BNUB2427-500

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Size / count 1x 500 µL

About this product

P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in malignant tumors of the prostate. As a result, p63 has been reported as a useful marker for differentiating benign from malignant lesions in the prostate, particularly when used in combination with markers of high molecular weight cytokeratins and the prostate-specific marker AMACR (P504S) . p63 has also been shown to be a sensitive marker for lung squamous cell carcinomas (SqCC), with a sensitivity of ~90%. Specificity for lung SqCC, vs. lung adenocarcinoma (LADC), is approximately 80%. In breast tissue, p63 has been identified in myoepithelial cells of normal ducts.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB2427-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Amplified in squamous cell carcinoma (AIS) ; Chronic ulcerative stomatitis protein (CUSP) ; EEC3; Keratinocyte transcription factor KET; LMS; NBP; p40; P51/P63; p53 like transcription factor; p53-related protein p63; RHS; SHFM4; TAp63alpha; TP53CP; TP53L; TP63; TP73; TP73L; Transformation-related protein 63; Trp53rp1; Trp6;3; Tumor protein 63; Tumor protein p53-like; tumor protein p73-like
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TP63
Gene ID
8626
NCBI Gene ID
137569
UniProt
Q9H3D4
Swiss Prot
Q9H3D4
Host
Mouse
Species Reactivity
Human
Reactivity
P63
Immunogen
Recombinant full-length human p63 protein
Target Antigen
p63
Clonality
Monoclonal
Clone
TP63/2427
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cell cycle, Tumor suppressors
Positive Control
HEK293 cells or Prostate Carcinoma or Lung or bladder squamous cell carcinoma
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
63 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL?

The catalog number for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL is BNUB2427-500.

What sizes are available for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL?

P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL in stock?

P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL?

P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL?

Estimated delivery time for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL?

The safety data sheet for P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is P63 (Squamous, Basal & Myoepithelial Cell Marker) (TP63/2427), 0.2mg/mL used for?

P63 is a homolog of the tumor suppressor p53. It is identified in basal cells in the epithelial layers of a variety of tissues, including epidermis, cervix, urothelium, breast and prostate. p63 was detected in nuclei of the basal epithelium in normal prostate glands; however, it was not expressed in

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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