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Product details
Catalog number BNUB2383-500
Price for BNUB2383-500
Size / count 1x 500 µL
CD40 is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is expressed on B-lymphocytes, follicular dendritic cells, bone marrow-derived dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zones of secondary lymphoid organs.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for CD40 / TNFRSF5 / CD40L-Receptor (C40/2383), 0.2mg/mL is BNUB2383-500.
CD40 / TNFRSF5 / CD40L-Receptor (C40/2383), 0.2mg/mL is available in the following size(s): 1x 500 µL.
CD40 / TNFRSF5 / CD40L-Receptor (C40/2383), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
CD40 / TNFRSF5 / CD40L-Receptor (C40/2383), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for CD40 / TNFRSF5 / CD40L-Receptor (C40/2383), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for CD40 / TNFRSF5 / CD40L-Receptor (C40/2383), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
CD40 is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AK
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.
