CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1888-100

Price for BNCB1888-100

Size / count 1x 100 µL

About this product

At least five CD1 genes (CD1a, b, c, d, and e) are identified. CD1 proteins have been demonstrated to restrict T cell response to non-peptide lipid and glycolipid antigens and play a role in non-classical antigen presentation. CD1a is a non-polymorphic MHC Class 1 related cell surface glycoprotein, expressed in association with Beta-2 microglobulin. Anti-CD1a labels Langerhans cell histiocytosis (Histiocytosis X), extranodal histiocytic sarcoma, a subset of T-lymphoblastic lymphoma/leukemia, and interdigitating dendritic cell sarcoma of the lymph node. When combined with antibodies against TTF-1 and CD5, anti-CD1a is useful in distinguishing between pulmonary and thymic neoplasms since CD1a is consistently expressed in thymic lymphocytes in both typical and atypical thymomas, but only focally in 1/6 of thymic carcinomas and not in lymphocytes in pulmonary neoplasms. Anti-CD1a is reported to be a new marker for perivascular epithelial cell tumor (PEComa) .Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB1888-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Cortical thymocyte antigen CD1A; Epidermal dendritic cell marker CD1a; FCB6; HTA1; T cell surface antigen T6 / Leu 6; T-Cell Surface Glycoprotein CD1A
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD1A
Gene ID: 909
NCBI Gene ID: 1309
UniProt: P06126
Swiss Prot: P06126
Host: Mouse
Species Reactivity: Human
Reactivity: CD1a|HTA1
Immunogen: Recombinant full-length human CD1a protein
Target Antigen: CD1a | HTA1
Clonality: Recombinant Monoclonal
Clone: RC1A/711
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: MOLT-4 cells. Paracortex in a tonsil or a reactive lymph node.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 49 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL?

The catalog number for CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL is BNCB1888-100.

What sizes are available for CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL?

CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL in stock?

CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL?

CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100b24/msds/bncb1888-100.pdf.

What is CD1a / HTA1 (Mature Langerhans Cells Marker) (rC1A/711), Biotin conjugate, 0.1mg/mL used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.