CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL — image 1 of 2

Product details

CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2083-100

Price for BNCB2083-100

Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 70 kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2083-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Activation B7-2 antigen; B lymphocyte activation antigen B72; CD28 antigen ligand 2; CD28LG2; CLS1; CTLA-4 counter-receptor B7.2; Early T-cell co-stimulatory molecule 1; ETC-1; FUN-1; LAB72; Ly-58; MB7-2; TS/A-2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD86
Gene ID: 942
NCBI Gene ID: 171182
UniProt: P42081
Swiss Prot: P42081
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Reactivity: CD86
Immunogen: Recombinant full-length human CD86 protein
Target Antigen: CD86
Clonality: Recombinant Monoclonal
Clone: RC86/1146
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research: Cancer immunotherapy/immune checkpoint, Immunology
Positive Control: 293T or Jukat cells. Monocytes and dendritic cells, activated T, B and natural killer cells in lymph node or tonsil.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL?

The catalog number for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL is BNCB2083-100.

What sizes are available for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL?

CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL in stock?

CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL?

CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e102135/msds/bncb2083-100.pdf.

What is CD86 (Dendritic Cells Maturation Marker) (rC86/1146), Biotin conjugate, 0.1mg/mL used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.