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Product details

Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2030-100

Price for BNCB2030-100

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Size / count 1x 100 µL

About this product

Beta-catenin associates with the cytoplasmic portion of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions. Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways, and is also found in complexes with many different proteins including the tumor suppressor protein APC. Defects in beta-catenin are associated with colorectal cancer, as well as many other cancer types. Beta-catenin is normally localized to the cell membrane, but can translocate to the nucleus in response to certain cell signaling. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2030-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Beta-catenin; Catenin beta-1; Catenin (Cadherin associated protein), beta 1; CTNNB
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CTNNB1
Gene ID
1499
NCBI Gene ID
476018
UniProt
P35222
Swiss Prot
P35222
Host
Rabbit
Species Reactivity
Human
Reactivity
Beta-catenin|Catenin, Beta
Immunogen
Recombinant full-length human Î2-catenin protein
Target Antigen
Beta-catenin | Catenin, Beta
Clonality
Recombinant Monoclonal
Clone
CTNNB1/2030R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Cell adhesion, Developmental biology, Signal transduction
Positive Control
HeLa or MCF-7 cells. Breast carcinoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
92 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL?

The catalog number for Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL is BNCB2030-100.

What sizes are available for Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL?

Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL in stock?

Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL?

Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Catenin, beta (CTNNB1) (CTNNB1/2030R), Biotin conjugate, 0.1mg/mL used for?

Beta-catenin associates with the cytoplasmic portion of E-cadherin. The catenin/cadherin complexes play an important role mediating cellular adhesion, including adherens junctions. Beta-catenin is involved in the Wnt signaling pathway as well as other signaling pathways, and is also found in complex

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

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