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Product details

Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2651-100

Price for BNCB2651-100

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Size / count 1x 100 µL

About this product

Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immuno-regulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2651-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cytokine Synthesis Inhibitory Factor (CSIF) ; GVHDS; IL-10; IL10; IL10A; Interleukin-10; T-cell Growth Inhibitory Factor (TGIF)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IL10
Gene ID
3586
NCBI Gene ID
193717
UniProt
P22301
Swiss Prot
P22301
Host
Rabbit
Species Reactivity
Human
Reactivity
Interleukin 10
Immunogen
Recombinant full-length human Interleukin 10 (IL10) protein
Target Antigen
Interleukin 10
Clonality
Recombinant Monoclonal
Clone
IL10/2651R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cytokines, Immunology, Inflammation
Positive Control
SK-BR3 Cells. Adrenal, Lymph Node, Bladder, Prostate or Endometrium.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
20 kDa (Monomer) ; 37 kDa (Dimer)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL?

The catalog number for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL is BNCB2651-100.

What sizes are available for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL?

Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL in stock?

Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL?

Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Interleukin 10 (IL10) (Immunoregulation Marker) (IL10/2651R), Biotin conjugate, 0.1mg/mL used for?

Interleukin 10 (IL10) is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immuno-regulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II antigens, and costimulatory molecules on macrophages

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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