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Product details

Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2897-100

Price for BNCB2897-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP accounts for >70% of their mass. Their shape is reminiscent of the nucleopore central plug. Treatment of cells with estradiol increases the amount of MVP in nuclear extract. The hormone-dependent interaction of vaults with ER is prevented in vitro by sodium molybdate. Antibodies to estrogen, progesterone and glucocorticoid receptors are able to co-immunoprecipitate the MVP. MVP is overexpressed in many neoplastic tissues and cell lines. Expression of MVP predicts a poor response to chemotherapy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2897-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Lung resistance-related protein (LRP) ; Major Vault Protein; MVP; VAULT1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MVP
Gene ID
9961
NCBI Gene ID
632177
UniProt
Q14764
Swiss Prot
Q14764
Host
Rabbit
Species Reactivity
Human
Reactivity
Major Vault Protein
Immunogen
Recombinant full-length human MVP protein
Target Antigen
Major Vault Protein
Clonality
Recombinant Monoclonal
Clone
VP2897R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Endocrinology
Positive Control
MCF-7 or HeLa cells. Breast tumors
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
104-110 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL?

The catalog number for Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL is BNCB2897-100.

What sizes are available for Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL?

Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL in stock?

Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL?

Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Major Vault Protein (MVP) (VP2897R), Biotin conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 104 kDa-110 kDa, characterized as major vault protein (MVP) . Vaults are large ribonucleoprotein particles (RNPs) present in all eukaryotic cells. They have a complex morphology, including several small molecules of RNA, but a single protein species. The MVP acc

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

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