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Product details
Catalog number BNCB1960-100
Price for BNCB1960-100
Size / count 1x 100 µL
This MAb recognizes a protein of 65 kDa, which is identified as glutamic acid decarboxylase 2 (GDA2) . It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GAD s) that are found in the brain: GAD2 (also known as GAD65) and GAD1 (also known as GAD67) . GAD1 and GAD2 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (ÃŽ3-aminobutyric acid) from L-glutamic acid. Although both GAD s are found in the brain, GAD2 localizes to synaptic vesicle membranes in nerve terminals, while GAD1 is distributed throughout the cell. A pathogenic role for GAD2 is identified in the human pancreas since it has been identified as an autoantibody and an auto-reactive T cell target in insulin-dependent diabetes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/1960), Biotin conjugate, 0.1mg/mL is BNCB1960-100.
GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/1960), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/1960), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/1960), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/1960), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for GAD2 / GAD65 (GABAergic Neuronal Marker) (GAD2/1960), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e101a51/msds/bncb1960-100.pdf.
This MAb recognizes a protein of 65 kDa, which is identified as glutamic acid decarboxylase 2 (GDA2) . It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. There are two forms of glutamic acid decarboxylases (GAD s) that are found in the brain: GAD2 (also
Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.
Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.
Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.
