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Product details

Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2368-100

Price for BNCB2368-100

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Size / count 1x 100 µL

About this product

This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A) . In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins) . Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2368-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
58kDa Cytokeratin; CK5; Cytokeratin-5; DDD1; Epidermolysis Bullosa Simplex 2 (EBS2) ; Keratin 5; Keratin, Type II Cytoskeletal 5; Keratin-5; KRT5; Type-II Cytoskeletal 5; Type-II keratin Kb5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT6A
Gene ID
3853
NCBI Gene ID
700779
UniProt
P02538
Swiss Prot
P02538
Host
Mouse
Species Reactivity
Human
Reactivity
Cytokeratin 6A
Immunogen
Recombinant full-length human Cytokeratin 6A (KRT6A) protein
Target Antigen
Cytokeratin 6A
Clonality
Monoclonal
Clone
KRT6A/2368
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
Tonsil or Basal Cell Carcinoma (BCC)
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
56 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL is BNCB2368-100.

What sizes are available for Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL?

Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL in stock?

Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL?

Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Cytokeratin 6A (KRT6A) (Basal Cell Marker) (KRT6A/2368), Biotin conjugate, 0.1mg/mL used for?

This MAb recognizes a protein of 56 kDa, identified as cytokeratin 6A (KRT6A) . In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

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