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Product details

MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1813-100

Price for BNCB1813-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase) . It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding MTAP is linked to the tumor suppressor gene, p16INK4A. Deficient levels of MTAP can occur in cancers primarily through co-deletion of the MTAP gene and the p16INK4A gene. Cells expressing MTAP and possessing adenine salvage pathway activity may be less susceptible to malignancy due to growth-inhibitory actions of agents (e.g. antifolates), whose mechanism of action, in part, involves this de novo purine pathway.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB1813-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BDMF; DMSFH; DMSMFH; Epididymis luminal protein 249; HEL249; LGMBF; MeSAdo phosphorylase; Methylthioadenosine phosphorylase; MSAP; MTA phosphorylase; MTAP; MTAPase; S-methyl-5''-thioadenosine phosphorylase
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MTAP
Gene ID
4507
NCBI Gene ID
193268
UniProt
Q13126
Swiss Prot
Q13126
Host
Mouse
Species Reactivity
Human
Reactivity
MTAP
Immunogen
Recombinant human MTAP protein fragment (aa97-196) (exact sequence is proprietary)
Target Antigen
MTAP
Clonality
Monoclonal
Clone
MTAP/1813
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
DNA repair
Positive Control
HepG2, A431, HeLa, HAP1 or MCF-7 cells. Kidney.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
31 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL?

The catalog number for MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL is BNCB1813-100.

What sizes are available for MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL?

MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL in stock?

MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL?

MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL?

The safety data sheet for MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MTAP (Tumor Suppressor Marker) (MTAP/1813), Biotin conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 31 kDa, which is identified as MTAP (5'-deoxy-5'-methylthioadenosine phosphorylase) . It catalyzes the reversible phosphorolysis of methylthioadenosine, which is important in polyamine metabolism and for the salvage of adenine and methionine. The gene encoding M

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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