- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
Product details
Catalog number BNCB2423-100
Price for BNCB2423-100
Size / count 1x 100 µL
BOB-1 is a transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2, boosting the promoter activity of those complexes. It is essential for the response of B-cells to antigens, required for the formation of germinal centers, and regilates IL-6 expression. BOB-1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB-1. Conversely, only some cases of classical Hodgkin lymphoma show BOB-1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB-1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for BOB.1 (B-Cell Marker) (BOB1/2423), Biotin conjugate, 0.1mg/mL is BNCB2423-100.
BOB.1 (B-Cell Marker) (BOB1/2423), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
BOB.1 (B-Cell Marker) (BOB1/2423), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
BOB.1 (B-Cell Marker) (BOB1/2423), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for BOB.1 (B-Cell Marker) (BOB1/2423), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for BOB.1 (B-Cell Marker) (BOB1/2423), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
BOB-1 is a transcriptional coactivator that specifically associates with either POU2F1/OCT1 or POU2F2/OCT2, boosting the promoter activity of those complexes. It is essential for the response of B-cells to antigens, required for the formation of germinal centers, and regilates IL-6 expression. BOB-1
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.
