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Product details

HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2207-500

Price for BNCB2207-500

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Size / count 1x 500 µL

About this product

This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60) . Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (HSPs), more appropriately called as stress response proteins (SRPs) . hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog. Clone rGROEL/780, unlike LK2, recognizes only the mammalian (not bacterial) hsp60 and is useful in distinguishing hsp60 from mammals and bacteria.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2207-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
60kDa chaperonin, 60kDa heat shock protein mitochondrial, Chaperonin, 60-KD (CPN60), GROEL, HLD4, HSP65, HSPD1, HuCHA60, Mitochondrial matrix protein P1, P60 lymphocyte protein, Short heat shock protein 60 Hsp60s1, Spastic paraplegia 13 (SPG13)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HSPD1
Gene ID
3329
NCBI Gene ID
595053
UniProt
P10809
Swiss Prot
P10809
Host
Mouse
Species Reactivity
Chicken, Cow, Dog, Drosophila Does not react with bacteria, Hamster, Intestinal Worm, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep, Xenopus
Reactivity
HSP60
Immunogen
Recombinant full-length human HSP60 protein
Target Antigen
HSP60
Clonality
Recombinant Monoclonal
Clone
RGROEL/780
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Autoimmunity, Heat shock proteins, Immunology, Inflammation
Positive Control
HeLa or HepG2 cells. Synovial biopsies from patients with juvenile chronic arthritis. Synovial lining layer is strongly positive for hsp60. Breast carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
60 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL?

The catalog number for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL is BNCB2207-500.

What sizes are available for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL?

HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL in stock?

HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL?

HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL?

The safety data sheet for HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is HSP60 (Heat Shock Protein 60) (Mitochondrial Marker) (rGROEL/780), Biotin conjugate, 0.1mg/mL used for?

This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60) . Its epitope is localized between aa 383-447 of human hsp60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock prote

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

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