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Product details

Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1969-500

Price for BNCB1969-500

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Size / count 1x 500 µL

About this product

Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticulation. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative. Adenocarcinomas of other-than-thyroid origin do not react with this antibody. This antibody is useful in identification of thyroid carcinoma of the papillary and follicular types. Presence of thyroglobulin in metastatic lesions establishes the thyroid origin of tumor. Anti-thyroglobulin, combined with anti-calcitonin, can identify medullary carcinomas of the thyroid. Furthermore, anti-thyroglobulin, combined with anti-TTF1, can be a reliable marker to differentiate between primary thyroid and lung neoplasms. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB1969-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
AITD3; hTG; TDH3; Tg; Tgn
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TG
Gene ID
7038
NCBI Gene ID
654591
UniProt
P01266
Swiss Prot
P01266
Host
Mouse
Species Reactivity
Human
Reactivity
Thyroglobulin
Immunogen
Human thyroid follicular cells
Target Antigen
Thyroglobulin
Clonality
Recombinant Monoclonal
Clone
R6E1
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer
Positive Control
Thyroid
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
660 kDa (Dimeric Form)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL?

The catalog number for Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL is BNCB1969-500.

What sizes are available for Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL in stock?

Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL?

Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Thyroglobulin (Thyroidal Cell Marker) (r6E1), Biotin conjugate, 0.1mg/mL used for?

Thyroglobulin is a 660 kDa dimeric pre-protein with mutiple glycosylation sites. It is produced by and processed within the thyroid gland to produce the hormone thyroxine and triiodothyronine. Prior to forming dimers, thyroglobulin monomers undergo conformational maturation in the endoplasmic reticu

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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