TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL — image 1 of 3

Product details

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2059-500

Price for BNCB2059-500

Size / count 1x 500 µL

About this product

VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15) . This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2059-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: TNF ligand-related molecule 1 (TL1A) ; Tumor necrosis factor (ligand) superfamily member 15 (TNFSF15) ; Vascular endothelial growth inhibitor 192a; Vascular endothelial growth inhibitor (VEGI) ; VEGI192A
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TNFSF15
Gene ID: 9966
NCBI Gene ID: 241382
UniProt: O95150
Swiss Prot: O95150
Host: Mouse
Species Reactivity: Human
Reactivity: TNFS15|VEGI
Immunogen: Recombinant full-length human VEGI protein
Target Antigen: TNFS15 | VEGI
Clonality: Recombinant Monoclonal
Clone: RVEGI/1283
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Angiogenesis, Cytokines
Positive Control: Endothelial cells. Colon, intestine, placenta, lung, liver, kidney, pancreas, spleen and prostate.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 22 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL?

The catalog number for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL is BNCB2059-500.

What sizes are available for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL?

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL in stock?

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL?

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL?

The safety data sheet for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (rVEGI/1283), Biotin conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.