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Product details

EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2968-500

Price for BNCB2968-500

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Size / count 1x 500 µL

About this product

This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2968-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Erbb1; ERBB1; Errp; HER1; mENA; PIG61; Proto-oncogene c-ErbB-1; Receptor Tyrosine Protein Kinase; ErbB1; Urogastrone; wa2; Wa5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
EGFR
Gene ID
1956
NCBI Gene ID
488293
UniProt
P00533
Swiss Prot
P00533
Host
Rabbit
Species Reactivity
Human
Reactivity
EGFR
Immunogen
Recombinant full-length human EGFR protein
Target Antigen
EGFR
Clonality
Recombinant Monoclonal
Clone
GFR/2968R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Signal transduction
Positive Control
A431 cells. Placenta, Breast, Colon or Bladder cancer
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~170 kDa (wild type) and ~145 kDa (vIII variant)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL?

The catalog number for EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL is BNCB2968-500.

What sizes are available for EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL?

EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL in stock?

EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL?

EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is EGFR (Epidermal Growth Factor Receptor) (GFR/2968R), Biotin conjugate, 0.1mg/mL used for?

This MAb recognizes a protein of 170 kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacell

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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