ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL — image 1 of 2

Product details

ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2900-500

Price for BNCB2900-500

Size / count 1x 500 µL

About this product

ATRX is a member of the Snf2 family of helicase/ATPases, which contribute to the remodeling of the nucelosome structure in an ATP-dependent manner, and facilitate the initiation of transcription and replication. Structurally, ATRX contains a PHD zinc finger motif. ATRX is regulated throughout the cell cycle where it is differentially distributed within the nucleus. During interphase, ATRX predominately associates with the nuclear matrix, while during mitosis, ATRX localizes with condensed chromatin. At the onset of M phase, phosphorylation rapidly induces this redistribution of ATRX to the short arms of human acrocentric chromosomes, where it then specifically complexes with heterochromatin protein 1 alpha to mediate chromosomal segregation. Mutations in the ATRX gene correlate with a high incidence of severe X-linked form of syndromal mental retardation associated with alpha-thalassemia or ATRX syndrome. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2900-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Transcriptional regulator ATRX; ATP-dependent helicase ATRX; RAD54 Homolog; X-linked helicase II; X-linked nuclear protein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: ATRX
Gene ID: 546
NCBI Gene ID: 533526; 653797
UniProt: P46100
Swiss Prot: P46100
Host: Rabbit
Species Reactivity: Human
Reactivity: ATRX
Immunogen: Recombinant full-length human ATRX protein
Target Antigen: ATRX
Clonality: Recombinant Monoclonal
Clone: ATRX/2900R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Cell cycle
Positive Control: Raji, HeLa or A431 Cells. Pancreas, Adrenal, Ovary, Kidney, Prostate or Stomach.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 280 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL?

The catalog number for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL is BNCB2900-500.

What sizes are available for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL?

ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL in stock?

ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL?

ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is ATRX / RAD54 (Alpha Thalassemia Mental Retardation) (ATRX/2900R), Biotin conjugate, 0.1mg/mL used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.