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Product details

Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2894-500

Price for BNCB2894-500

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Size / count 1x 500 µL

About this product

Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta-IV) and a beta-H subunit creating diversity and specialization of function. Spectrin alpha and spectrin beta are present in erythrocytes, whereas spectrin alpha II (also designated fodrin alpha) and spectrin beta I (also designated fodrin beta) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. Spectrin beta III is highly homologous to both spectrin beta I and spectrin beta II. Spectrin beta III is highly expressed in brain, kidney, pancreas and liver, and at lower levels in lung and placenta. Spectrin beta 3 is primarily expressed in nervous tissues with highest expression levels in the cerebellum, where it is found in Purkinje cell soma and dendrites.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2894-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Beta III spectrin; SCA5; Spectrin beta chain brain 2; Spectrin beta non-erythrocytic 2; Spectrin non-erythroid beta chain 2; Spinocerebellar ataxia 5; SPTBN2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SPTBN2
Gene ID
6712
NCBI Gene ID
26915
UniProt
O15020
Swiss Prot
O15020
Host
Rabbit
Species Reactivity
Human
Reactivity
Spectrin Beta-III
Immunogen
Recombinant human SPTBN2 fragment (aa356-475) (exact sequence is proprietary)
Target Antigen
Spectrin Beta-III
Clonality
Recombinant Monoclonal
Clone
SPTBN2/2894R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Cytoskeleton
Positive Control
HeLa cells. Pancreas or Liver.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
246 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL?

The catalog number for Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL is BNCB2894-500.

What sizes are available for Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL?

Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL in stock?

Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL?

Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Spectrin beta III (SPTBN2) (SPTBN2/2894R), Biotin conjugate, 0.1mg/mL used for?

Spectrin is an actin binding protein that is a major component of the plasma membrane skeleton. Spectrins function as membrane organizers and stabilizers by forming dimers, tetramers and higher polymers. Vertebrate spectrins have two alpha-subunits (alpha-I/alpha-II), four beta-subunits (beta-I-beta

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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