PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2969-500

Price for BNCB2969-500

Size / count 1x 500 µL

About this product

This antibody recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is localized between aa57-84 of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60% of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2969-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BCEI, Breast Cancer Estrogen Inducible Protein, Gastrointestinal Trefoil Protein, Gastrointestinal trefoil protein pS2, HP1A, HPS2, pNR2, TFF1, Trefoil Factor 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TFF1
Gene ID: 7031
NCBI Gene ID: 162807
UniProt: P04155
Swiss Prot: P04155
Host: Rabbit
Species Reactivity: Cynomolgus, Human
Reactivity: PNR-2|pS2|TFF1
Immunogen: Synthetic peptide of 28 amino acid residues corresponding to CFDDTVRGVPWCFYPNTIDVPPEEECEF (aa57-84) from the C-terminus of human pS2.
Target Antigen: pNR-2 | pS2 | TFF1
Clonality: Recombinant Monoclonal
Clone: TFF1/2969R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Endocrinology
Positive Control: Breast or Ovarian carcinoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 6.5 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL?

The catalog number for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL is BNCB2969-500.

What sizes are available for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL?

PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL in stock?

PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL?

PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PS2 / pNR-2 / TFF1 (Estrogen-Regulated Protein) (TFF1/2969R), Biotin conjugate, 0.1mg/mL used for?

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.