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Product details

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2052-500

Price for BNCB2052-500

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Size / count 1x 500 µL

About this product

VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15) . This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2052-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
TNF ligand-related molecule 1 (TL1A) ; Tumor necrosis factor (ligand) superfamily member 15 (TNFSF15) ; Vascular endothelial growth inhibitor 192a; Vascular endothelial growth inhibitor (VEGI) ; VEGI192A
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TNFSF15
Gene ID
9966
NCBI Gene ID
241382
UniProt
O95150
Swiss Prot
O95150
Host
Rabbit
Species Reactivity
Human
Reactivity
TNFS15|VEGI
Immunogen
Recombinant full-length human VEGI protein
Target Antigen
TNFS15 | VEGI
Clonality
Recombinant Monoclonal
Clone
VEGI/2052R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Angiogenesis, Cytokines
Positive Control
Endothelial cells. Colon, intestine, placenta, lung, liver, kidney, pancreas, spleen and prostate.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
22 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL?

The catalog number for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL is BNCB2052-500.

What sizes are available for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL?

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL in stock?

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL?

TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TNFS15 / VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/2052R), Biotin conjugate, 0.1mg/mL used for?

VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15) . This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a l

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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