CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1953-500

Price for BNCB1953-500

Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 140 kDa, which is identified as the complement receptor 2 (CR2) / CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB1953-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD21; Complement C3d receptor (C3DR) ; Complement Receptor type 2 (CR2) ; CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CR2
Gene ID: 1380
NCBI Gene ID: 445757
UniProt: P20023
Swiss Prot: P20023
Host: Mouse
Species Reactivity: Human
Reactivity: CD21
Immunogen: Recombinant human CR2 (CD21) protein fragment (around aa 44-196) (exact sequence is proprietary)
Target Antigen: CD21
Clonality: Monoclonal
Clone: CR2/1953
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Immunology
Positive Control: WEHI-231 cells. Human tonsil tissue.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 140 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL?

The catalog number for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL is BNCB1953-500.

What sizes are available for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL in stock?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL?

CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) (CR2/1953), Biotin conjugate, 0.1mg/mL used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.