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Product details

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2167-500

Price for BNCB2167-500

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Size / count 1x 500 µL

About this product

Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized by slowly progressing contractures, skeletal muscle wasting and cardiomyopathy. Reportedly, lack of Emerin expression is one cause of EDMD. Emerin is involved in the association of the nuclear membrane with the lamina, and is localized specifically to desmosomes and fasciae adherents in the heart. Identification of nuclear membrane irregularities with anti-emerin antibody has been reported useful in diagnosing papillary thyroid carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2167-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
EMD; Emerin; Emery Dreifuss muscular dystrophy (EDMD) ; STA
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
EMD
Gene ID
2010
NCBI Gene ID
522823
UniProt
P50402
Swiss Prot
P50402
Host
Mouse
Species Reactivity
Human
Reactivity
Emerin
Immunogen
Recombinant human Emerin protein fragment (around aa 56-167) (exact sequence is proprietary)
Target Antigen
Emerin
Clonality
Monoclonal
Clone
EMD/2167
Type
Primary
Source
Animal
Origin
Animal
Applications
IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Organelle markers
Positive Control
K-562, HeLa or Jurkat cells. Kidney or Skin
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
37 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL?

The catalog number for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL is BNCB2167-500.

What sizes are available for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL in stock?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL?

Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Emerin (Papillary Thyroid Carcinoma and EDMD Marker) (EMD/2167), Biotin conjugate, 0.1mg/mL used for?

Emerin is a member of the nuclear lamina associated protein family. It is ubiquitously expressed and localized to the nuclear membrane in normal cells. Mutations of the gene that encodes emerin result in the X-linked recessive disease Emery-Dreifuss muscular dystrophy (EDMD), which is characterized

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

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