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Product details
Catalog number BNCB2391-500
Price for BNCB2391-500
Size / count 1x 500 µL
This MAb recognizes a protein of 67 kDa, which is identified as glutamic acid decarboxylase 1 (GDA1) . There are two forms of glutamic acid decarboxylases (GADs) that are found in the brain: GAD65 (also known as GAD2) and GAD67 (also known as GAD1. GAD65 and GAD67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate-limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GAD s are found in the brain, GAD65 localizes to synaptic vesicle membranes in nerve terminals, while GAD67 is distributed throughout the cell. GAD67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD65 will transiently activate to assist in GABA production. The loss of GAD65 is detrimental and can impair GABA neurotransmission, however the loss of GAD67 is lethal. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for GAD1 / GAD67 (GABAergic Neuronal Marker) (GAD1/2391), Biotin conjugate, 0.1mg/mL is BNCB2391-500.
GAD1 / GAD67 (GABAergic Neuronal Marker) (GAD1/2391), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
GAD1 / GAD67 (GABAergic Neuronal Marker) (GAD1/2391), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
GAD1 / GAD67 (GABAergic Neuronal Marker) (GAD1/2391), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for GAD1 / GAD67 (GABAergic Neuronal Marker) (GAD1/2391), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for GAD1 / GAD67 (GABAergic Neuronal Marker) (GAD1/2391), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
This MAb recognizes a protein of 67 kDa, which is identified as glutamic acid decarboxylase 1 (GDA1) . There are two forms of glutamic acid decarboxylases (GADs) that are found in the brain: GAD65 (also known as GAD2) and GAD67 (also known as GAD1. GAD65 and GAD67 are members of the group II decarbo
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
